The Effect of Ankle-Foot Orthoses on Gait Characteristics in People with Charcot-Marie-Tooth Disease: A Systematic Review and Meta-Analysis

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aut.relation.articlenumbere70003
aut.relation.issue3
aut.relation.journalJournal of Foot and Ankle Research
aut.relation.volume17
dc.contributor.authorKim, Andrew
dc.contributor.authorFrecklington, Mike
dc.contributor.authorPhilps, Adam
dc.contributor.authorStewart, Sarah
dc.date.accessioned2024-09-15T23:49:45Z
dc.date.available2024-09-15T23:49:45Z
dc.date.issued2024-09-14
dc.description.abstractIntroduction Ankle-foot orthoses (AFOs) are commonly prescribed for people with Charcot-Marie-Tooth disease (CMT) to improve gait efficiency and reduce the occurrence of tripping and falls. The aim of this study was to systematically review evidence on the effects of AFOs on gait kinematics and kinetics and postural stability/balance in people with CMT. Methods Studies were identified from electronic databases and screened for inclusion online using Rayyan. Data from all eligible studies were extracted into a standardised Excel spreadsheet. Methodological quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklists. Where available, continuous outcomes were pooled to estimate standardised mean differences in random-effects meta-analyses. Results A total of 15 studies were included with variable methodological quality. Sample sizes ranged from 1 to 32 with significant variability in participant characteristics, AFO designs and testing procedures. Data from eight studies were available for meta-analysis. Although AFOs impacted walking velocity, stride length, step length, cadence, ankle dorsiflexion, plantarflexion, knee and hip flexion and ankle plantarflexion and dorsiflexion moments, the effect sizes were small-to-moderate and non-significant. There were insufficient data available for pooled analyses of outcomes related to postural stability/balance. Conclusion Although AFOs positively affect a number of gait and balance parameters, the small participant numbers, variability in participant characteristics, AFO designs and testing procedures adopted by the available studies resulted in the absence of statistically significant effects when data were pooled. The results from this review also highlight the importance of device customisation based on the individual needs of people with CMT and their degree of gait impairment.
dc.identifier.citationJournal of Foot and Ankle Research, ISSN: 1757-1146 (Print); 1757-1146 (Online), BMC, 17(3). doi: 10.1002/jfa2.70003
dc.identifier.doi10.1002/jfa2.70003
dc.identifier.issn1757-1146
dc.identifier.issn1757-1146
dc.identifier.urihttp://hdl.handle.net/10292/18015
dc.languageen
dc.publisherBMC
dc.relation.urihttps://onlinelibrary.wiley.com/doi/10.1002/jfa2.70003
dc.rights© 2024 The Author(s). Journal of Foot and Ankle Research published by John Wiley & Sons Australia, Ltd on behalf of Australian Podiatry Association and The Royal College of Podiatry. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.rights.accessrightsOpenAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject1103 Clinical Sciences
dc.subject1104 Complementary and Alternative Medicine
dc.subject1106 Human Movement and Sports Sciences
dc.subject3202 Clinical sciences
dc.subject4201 Allied health and rehabilitation science
dc.subject4207 Sports science and exercise
dc.titleThe Effect of Ankle-Foot Orthoses on Gait Characteristics in People with Charcot-Marie-Tooth Disease: A Systematic Review and Meta-Analysis
dc.typeJournal Article
pubs.elements-id569074
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